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Fructose in excess is a slow acting poison
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Fructose in excess is a slow acting poison
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Basics on sugar, fructose, metabolism, and glycation

Still Tripod is not compatible with MS word From about 2018, this post is 12/31/2023

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Chapter 1: Basics on sugars, fructose, metabolism, glycation: 1. Introduction 2. Chemistry of fructose 3. All about fructose 4. Sugars, fats, etc. 5. Insulin resistance 6. The Yudkin and Keys examples 7. Know the villain.
Three YouTube video and a large video library
Basics of Metabolism 6 minutes at https://www.youtube.com/watch?v=pNzFYBA2Ofg a must to know what is covered in this and next section. Learn about the Krebs (citric acid) cycle), how the body converts glucose and fatty into usable energy. Electron Transport Chain 2 min https://www.youtube.com/watch?v=AGaxa5Kjvx8 on how the energy from the Krebs cycle is used in the electron transport chain to convert ADP to ATP (by adding one phosphate group). ATP is the gasoline of our body. Sugar Explained, 20 min, https://www.youtube.com/watch?v=f_4Q9Iv7_Ao, and for fun on why we get fat, just 3 minutes at https://www.youtube.com/watch?v=mNYlIcXynwE. My video library at http://healthfully.org/rh/id7.html; there are over 500 links to YouTube on 23 topics with ratings, over half on diet related topics. The video library collection is also at /rg and /rc. With taking notes, three areas of the brain, sound, vision, and writing are engaged. The more parts of the brain utilized, the greater the rate of learning.
I would place Jason Fung and Garry Taubes as the most knowledgeable writers on why humans are the sickest of mammals. Fung is the nephrologist with thousands in his dietary health program. He focuses on biology and diet. Taubes is the award-winning science writer, a cross between investigator and storyteller. Taubes will use a chapter to explain the effects of slow roasting tobacco to make it mild by converting fiber to sugar and another chapter on the health of paleo populations in his Case Against Sugar. He develops history, Fung science. I stand on their shoulders. You can see through my eyes the complex landscape, like the collection of Hieronymus Bosh (c. 1450 to 1516) paintings of earth, heaven, and hell (see painting below). I paint the fructonic plague and its corporate devils, Nestles, Kraft-Heinz, Gerber, the sugar associations, university nutrition departments, pharma and their scientists for hire (KOLs), governments, and banksters. They have made us the sickest of mammals, and next generations increasingly sicker.
This chapter covers the chemical foundation of why and how sugar fructose is worse than ethanol and ends with scientists for hire promoting sugar as harmless empty calorie and it is your fault. It is on a college freshman’s level, for physicians, researchers, and those with the basics in chemistry. It presents the evidence for the case against fructose. The subsequent chapters are significantly easier reading material but for 3 on MTD.
There is a beauty in the complexity of mammalian life; I wish to share it with you. I wish to guide you through the corporate minefield. Read on and take notes and immerse yourself in the topics, watch the videos in my library that are on YouTube. Become an expert; It’s for your health and those you influence.

Key points
1 Glycation is the non-enzymatic bonding of a 5 or 6 carbon sugar to an electron donor.
2 Fructation is fructose glycating.
3 The reducing sugars when in the open chain formation (not ring formation) will bond to electron donors.
4 Fructose is 32-times longer in the open chain formation than glucose, thus its rate of glycation is 32-times greater than glucose.
5 From the reaction of fructation it has “300 times as many highly reactive chain structures as glucose.”
6 The glycated reducing sugars are converted by the Maillard reaction into dicarbonyls-- mainly methylglyoxal--which are thousands of times more reactive.
7 Fructose’s derivates form dicarbonyls which are produced at a rate three-hundred times greater rate than from glucose.
8 Fasting fructose in the blood is about 1/10th that of fasting glucose.
9 Over 3-hours following a 75 bolus of sucrose, the blood level of fructose is double that of glucose; fructose glycating the endothelial cells in arteries is a major CC to atherosclerosis and its pathogenic consequences ischemic events mainly MI and strokes.
10 The Krebs cycle (citric acid cycle) in the mitochondria adds a third phosphate to ADP to become ATP which is the major cellular energy molecule.
11 The Krebs cycle metabolizes the pyruvate from sugars to produce ATP (adenosine triphosphate) from ADP (adenosine diphosphate) by addition of a phosphate (PO4).
12 Glucose and fructose are converted to three carbon 2-pyruvate molecules in the cytosol then the pyruvate is transported into the MTD to power the Krebs-cycle’s production of ATP.

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