Obesity

Obesity & cancer deaths up over 60%
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Obesity & cancer deaths up over 60%

Fattest group BMI of >40 had a men 52% & women 62% greater risk of dying of cancer than those of normal weight.  This supports the Scientific American chart which shows an increase as the BMI increases

The New England Journal of Medicine

established in 1812. april 24, 2003, vol. 348 no. 1

http://74.125.155.132/scholar?q=cache:eerFpGGA1FcJ:scholar.google.com/+cancer+survival+%2B+aspirin&hl=en&as_sdt=0,5

 

Overweight, Obesity, and Mortality from Cancer in a Prospectively

Studied Cohort of U.S. Adults

Eugenia E. Calle, Ph.D., Carmen Rodriguez, M.D., M.P.H., Kimberly Walker-Thurmond, B.A., and Michael J. Thun, M.D

Background

The influence of excess body weight on the risk of death from cancer has not been fully

characterized

 

Methods

In a prospectively studied population of more than 900,000 U.S. adults (404,576 men

and 495,477 women) who were free of cancer at enrollment in 1982, there were 57,145

deaths from cancer during 16 years of follow-up. We examined the relation in men and

women between the body-mass index in 1982 and the risk of death from all cancers

and from cancers at individual sites, while controlling for other risk factors in multivari-

ate proportional-hazards models. We calculated the proportion of all deaths from can-

cer that was attributable to overweight and obesity in the U.S. population on the basis of

risk estimates from the current study and national estimates of the prevalence of over-

weight and obesity in the U.S. adult population

 

Results

The heaviest members of this cohort (those with a body-mass index [the weight in kilo-

grams divided by the square of the height in meters] of at least 40) had death rates from

all cancers combined that were 52 percent higher (for men) and 62 percent higher (for

women) than the rates in men and women of normal weight. For men, the relative risk

of death was 1.52 (95 percent confidence interval, 1.13 to 2.05); for women, the relative

risk was 1.62 (95 percent confidence interval, 1.40 to 1.87). In both men and women,

body-mass index was also significantly associated with higher rates of death due to

cancer of the esophagus, colon and rectum, liver, gallbladder, pancreas, and kidney; the

same was true for death due to non-Hodgkin’s lymphoma and multiple myeloma. Signif-

icant trends of increasing risk with higher body-mass-index values were observed for

death from cancers of the stomach and prostate in men and for death from cancers of

the breast, uterus, cervix, and ovary in women. On the basis of associations observed in

this study, we estimate that current patterns of overweight and obesity in the United

States could account for 14 percent of all deaths from cancer in men and 20 percent of

those in women.

 

conclusions

Increased body weight was associated with increased death rates for all cancers com-

bined and for cancers at multiple specific sites

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