There has
been in the last 3 years numerous changes and additions to the healthful
website as JK realized the extent of corruption worked by pharma on the
evidence base. Major revision in
causes
of heart disease.
Two Changes
in content coming up
The cholesterol myth. Numerous
critics have pointed out that cardiovascular
disease is not caused by higher levels of blood cholesterol or fats. Pharma
promotes the cholesterol myth and
ignores the major causes. Major cause of cardiovascular
disease is
pathogens living within the middle layer of artery walls. It initiates the immune
response which involves
LDL, HDL, and white blood cells.
Reactive chemicals such as simple sugars and carbon monoxide can
potentiate the process resulting in the formation of plaque within the artery
walls.
For confirmation from journal articles on primary
role of
infective agent enter into http://scholar.google.com/
terms such as bacteria + atherosclerosis
or go to http://healthfully.org/rl/id8.html
and id9 for
collection of articles
For confirmation of cholesterol myth enter into
http://scholar.google.com/ or http://www.amazon.com/ cholesterol myth, or go to http://healthfully.org/rl/id5.html
for collection of journal articles.
The article
below was done in 2009, before JK discovered the extent of the corruption
worked by pharma. Much of what has
been
stated here was based upon a reliance of pharma’s opinion leaders.
The recommended section of this website has a
far better analysis—see http://healthfully.org/rc/
< less than > greater than Date HDL LDL Chol LDL/HDL Chol/HDL Triglycer ides Blood Pressure Fasting glucose 1 >40 <130 <200 >6.0 high <3.0 low <130 <200 30-110 >130 >110 2 M-good >60 <100 3-6 high <150 >130 >110 3 Desirable >40 100-129 <200 <150 4 borderline 130-159 200-239 150-199 Row 1 from blood
work; rows 2, 3 & 4 from Merck
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Age 20-34 35-39 40-44 45-49 50-54 55-59 60-64 65-69 70-74 75-79 Age points -7 -3 0 3 6 8 10 12 14 16 TC <160 0 0 0 0 0 0 0 0 0 0 160-199 4 4 3 3 2 2 1 1 1 1 200-239 8 8 6 6 4 4 2 2 1 1 240-279 11 11 8 8 5 5 3 3 2 2 >280 13 13 10 10 7 7 4 4 2 2 Nonsmoker 0 0 0 0 0 0 0 0 0 0 Smoker 9 9 7 7 4 4 2 2 1 1 HDL>60 -1 50-59 0 40-49 1 <40 2 BP <120 Untreated 0 Treated 0 120-129 Untreated 1 Treated 3 130-139 Untreated 2 Treated 4 140-159 Untreated 3 Treated 5 >160 Untreated 4 Treated 6 POINTS (10 yr. Risk of MI or CAD death
%): <9 point = 1%; 9-12
= 1%; 13-14 = 2%; 15 = 3%; 16 = 4%; 17 = 5%; 18 = 6%;
19 = 8%; 19 = 8%; 20 = 11%;
21 = 14%;
22 = 17%; 23 = 22%;
24 = 27%; 25 = >30% < less than
> greater than HEART STATS American Heart Association For tables of heart disease factors (43
pages—would copy to web page) http://www.americanheart.org/downloadable/heart/1200078608862HS_Stats%202008.final.pdf Fat consumption is 33% of total calories
with saturated fats being 10.8%. Meat averages 200 pounds per person per year. Catheterizations 1,322,000 annually,
604,502 hospital discharges, with average stay of 3.6 days. In 05 there were
469,000 coronary artery bypass procedures preformed on 261,000 patients. In 06 2,192 heart transplants, with 24.7 were younger
than 35. 1,265,000 Percutaneous Coronary Interventions (PCI) (angioplasty). Costs for 04 were for bypass $85,653, PCI $44,110; Catheterization $25,322, pacemaker
$43,101; implantable defibrillator $99,845, endarterectomy $22,037, valves $119,918.
Since 1965 smoking has declined 50%.
Smoking was 43.2% for those with 9-11 years of education and 7.1% for those with more than 16 years. 46,600,000 smokers in 05 (25.9 males and 20.7 females). From 1997-2001, an estimated 438,000
Americans died each year of smoking-related illnesses, of which 34.7% were from cardiovascular disease. On an average, male smokers
die 13.2 years earlier than nonsmokers and females 14.5 years earlier than female nonsmokers. Smoking caused 3.3 million years of lost for men, and 2.2 million for women. Cigarette smoking results in a two-to-three-fold risk of dying from coronary heart disease. Use of tobacco products in 2004 was 31.4% for whites, 11.7% for Asians, 23.3% for Latinos. In 2005 106,700,000 had total cholesterol
of 200 mg/dL (age 20 and older), or 48%, and for above 240 mg/dL, 37,200,000 or 17%. Overweight children 2-5 years 10.3%
were overweight in 04; 6-11 years increased from 4% in 71 to 17.5% in 04. ADULTS,
142,000,000 were overweight (73M males, and 69M females) which is 66% of adult population, of which 31.4% were obese BMI of
30 or greater). Diabetes mortality in 04 was 225,400, which is 2-4 times higher
than those without diabetes. Lifetime risk of stroke goes from 1.8 to 6%. High blood pressure in 05, 73M (1
in 3 adults), (33.4M men, 39M women) untreated systolic pressure of 140 mm Hg or higher, or diastolic pressure of 90 mm HG
or higher. This results in a 1.5 times greater rate of heart disease and a 4.2 times rate of end-stage kidney disease. Elder women (over 75) have an 83.8 incidence and men a 69.5% incidence
of CORONARY HEART DISEASE ( From Wikipedia.org: About one half the smokers will die of illnesses due to smoking. A
world-wide a billion people this century will die this century from the health consequences of tobacco. 1,205 Big PhARMA claims that it is the drugs
which prolong life, but rather it is the reduction in cardiovascular disease, and this is attributed in the main to the reduction
in the smoking rate—whose major impact upon the stats takes 20 years. Smoking
reached a high of 59% of the male and 46% percent of the female adult population in the early 50s. It currently is at 27 & 22% respectively (MORE PROOF THAT WOMEN Coronary death rate Women Men 21 0-19 23 51 20-29 110 300 30-39 889 1,538 40-49 4,767 3,857 50-59 11,240 7,989 60-69 16,117 17,997 70-79 24,082 49,294 80 + 32,282 Annual
death rate from coronary heart disease Placing
a stent (angioplasty) in artery takes about 30 minutes. Genetic
factor MEF2A codes for a protein that makes up part of the cell’s membrane. When
mutated the risk factor for coronary is over 95%. Other
genes are being found, such as apoE4, which is involved in arterial inflammation. There
is a mechanism whereby to deal with arterial inflammation plaque forms in affected areas.
This mechanism is mediated by white blood cells. Vioxx and all the Sudden
death from heart attack, without significant prior symptoms, occurs in 59% of men and 64% of women. Coronary
artery walls are about a millimeter thick and flex about 70 times a minute as the heart pumps.
It is thus tough to get a clear image of how occluded. An angiography
(where a die is injected into the blood vessel, can only show how much blood is flowing through the artery, and not the plaque
embedded in the wall. Computed tomography (CT) scanner (a 3-dimensional x-ray
machine) can produce striking images, however, it is too risky, and costly for standard screening. Risk Factors Factor Results Poor ratio of 4x Diabetes 4x women 2x men Hypertension 2x women 3x men Stress & depression* 3x 3x Healthy diet - 30% Abdominal obesity 2x Lack of exercise + 20% Smoking long term 2x (1 pack) THE
CHOLESTEROL PROCESS: 1.
Cholesterol in the bloodstream
infiltrates the arterial wall 2.
Immune system dispatches
macrophages to consume the cholesterol. The bloated macrophages become foam cells. 3.
Foam cells accumulate
to become a major component of the plaque. 4.
To keep the arterial
walls slick and smooth muscle cells form a cap. 5.
Foam cells in the plaque
secrete chemicals that weaken the cap. 6.
When the cap cracks,
plaque seeps into the bloodstream, and can form a clot which can block the flow of blood. 7.
Inflammation process
is believed to soften the plaque. Those who have a financial interest in the outcome manipulate the results, Major study finds that all 37 journal articles positive effects over stated; the average was 32%. Statins cause erectile
dysfunction, cognitive imparement, and cancer. Lipitor (2011) lifetime sales $131
billion, tops all drugs. Plavix at
$60 billion is second. STATINS CANCER Link 52% short term LA Times, Health section, Vytorin, the
combination drug (simvastatin (better known by its commercial name Zocor) and ezetimibe--known as Zetia) prescribed to lower
cholesterol, sustained another blow today, when the author of a major clinical trial announced that the medication had failed
to drive down hospitalization and death due to heart failure in patients with narrowing of the aortic valve. In the process,
researchers in Today's findings
suggested something more ominous: the incidence of cancer -- and of dying of cancer -- was significantly higher in the patients
taking Vytorin. Altogether, 67 patients on placebo developed cancer during the trial.
Among subjects on Vytorin, 102 developed cancers of various kinds.* This
is the second adverse press—the first being in March 08, when the ENHANCE trial found that Vytorin fared no better than
a placebo at reducing plaque buildup on the walls of patients' arteries.* * Comments
by jk Simvastatin (Zocor) is off patent. Thus in a scramble for profits a combination drug (on patent) was introduced. Direct to consumer market cost $155 in 07—mainly TV ads. *
The pressing issue is that since the development of Statins, the very
first animal studies in the 60s it has been known that Statins increase the incidents of cancer. However, nearly all studies done thereafter have not included cancer.
*
Several studies have failed to find a reduction in the build of plaque, even thought the statins including Zocor, reduce
EXTENDED RELEASE NIACIN IS A SAFER, AND A MORE EFFECTIVE WAY TO LOWER
MI RISK! |