Recommended Non-technical Dietary--JK

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On Fructose causing Obesity and Diabetes and fix

On Fructose Causing Obesity & Diabetes12/23/16

I am near the end of my 3-year research into how our Western high-sugar diet causes diabetes and obesity pandemics along with their many comorbidities including cardiovascular disease (CVD), Alzheimer’s disease, and osteoarthritis.  The evidence is convincing, so industry opposes it with their tobacco science that is repeated by physicians and corporate media is silent.  The obvious is ignored:  Like all mammals we have a complex weight-regulatory system that is screwed up by the western diet.  The science reveals that too much fructose (one-half of the disaccharide sucrose, table sugar) starts this process leading to metabolic dysfunctions.  It starts with glycation, the random attachment of a sugar to a protein, which thereby can hinder to functions of that protein.   Since fructose is only metabolized in the liver it accumulates there and damages the Liver more so than other organs.  It appears that fructose and galactose [from milk] have over in vivo ten times the glycation activity of glucose, the primary body fuel” Wiki.  The western diet is very high in sugar (one half of which is fructose).  In 2001 the FDA listed the averages consumption at 121 pound years.  That means that half of American are consuming more than average.  This combination of high sugar diet and the damage caused by fructose through glycation is why Prof. Robert Lustig calls sugar poison.  The damage it does through glycation in the liver starts the process leading to insulin resistance, non-alcoholic fatty liver disease, diabetes, obesity, our high incidence of cardiovascular disease and much more.  


Glycation is the first step in the evolution of these molecules through a complex series of very slow reactions in the body known as Amadori reactionsSchiff base reactions, and Maillard reactions; which lead to advanced glycation end products (AGEs). Some AGEs are benign, but others are more reactive than the sugars they are derived from, and are implicated in many age-related chronic diseases such as cardiovascular diseases (the endothelium, fibrinogen, and collagen are damaged), Alzheimer's disease (amyloid proteins are side-products of the reactions progressing to AGEs),[7][8] cancer (acrylamide and other side-products are released), peripheral neuropathy (the myelin is attacked), and other sensory losses such as deafness (due to demyelination). This range of diseases is the result of the very basic level at which glycations [1] interfere with molecular and cellular functioning throughout the body and [2] the release of highly oxidizing side-products such as hydrogen peroxideWiki.  Since 99% of fructose is metabolized in the liver, it accumulates there, thus the liver is subjected to the most damage of any organ by glycation.  Damage by fructose is one hit upon the liver. 

The second hit comes from fat accumulation.  When the liver is overloaded with glucose and fructose from a meal high in starches and sugars, they are converted to fats.  However, only 20% of glucose goes to the liver, compared to 99% of fructose, thus high sugar snacks including fruit juices plays a greater role a major role in the storage of fat in the liver and also glycation.  When the liver accumulates an extra 2 or 3 pounds of fat, it function of regulating blood sugar (glucose) is hindered.  Then insulin which also functions to lower blood glucose, must be secreted in a higher than normal level.  Insulin functions to cause the body to burn glucose and thus to stop burning fat and store it.  Thus higher than normal insulin is what causes the stead weight gain that results in obesity.  All this starts with the double whammy of glycation and fatty liver.  The NHANES study found that over 30% of adults have excess fat storage in the liver (non-alcoholic fatty liver disease, NAFLD), a serious medical condition that can progress to cirrohosis of the liver.  

It takes the combination of both fructose & glucose.  This explains why the Orientals on a traditional diet do not have a weight problem:  their diet is high in refined carbs (glucose) and is very low in sugar.  Those who deviate with added sugars get fat.  Fat also accumulates in the pancreas, and in excess reduces the production of insulin to cause type-2 diabetes (T2D).  Obesity and T2D are caused by diet and can be fixed by diet. 

The fix for the long-term over weight is to remain in the fat burning mode.  Since both proteins and glucose (carbs) cause insulin secretion, simply eating less will not keep the dieter in the fat burning mode.  Moreover, the hormone leptin secreted by fat (adipose) tissue will function to restore weight by reducing metabolism 25% or more, this will increases appetite by making the dieter desire food to feel better.  When we are sleeping the small store of glucose & glycogen is burnt, than the body switches to metabolizing stored fat.  By not eating when getting up, fat burning continues.  Fasting is the fix for the accumulated fat in the liver, pancreas, and adipose tissue.  The scientific literature is clear on this fix.  The most successful for those who are obese or have type-2 diabetes is alternate day fasting.  Less series cases can simply skip their breakfast, the short-term fast.  I have prepared a number of papers on what to eat, and fasting.  There are five recommended diets depending on the health situation at Cleansing Diet and what to eat, and much more at its long version.   Our metabolic system has evolved for short-term lack of food thus fasting is easy.   While sleeping the cells during fat metabolism undergo repair, one main system is autophagy.  Thus fasting and ketogenic diet (very low carbs) promote healing.  By extending the healing process, the risk for the diseases of the western diet are very significantly reduced.  This fact has resulted in my going a ketogenic diet at least one week a month, and to 6 out of 7 days a week skipping breakfast.  These two changes has resulted in a loss of 6 pounds, I am now as lean as when I graduated high school in 1962, and I have the energy for weight training, running once a week 2 miles, and swimming at least twice a week a half mile.  Cardiovascular fitness is strongly associated with avoiding age-related conditions.    



To reduce glycation damage I avoided foods with added sugar, and limit my whole fruits to 1 portion per day.  I also take3 antioxidants 1,000 mg of the antioxidant Q10, and 500 mg of vitamin C.  One is fat soluble, the other water, thus they protect both fluids where sugar and its targets for glycation occur.  I also take a second powerful antioxidant, glutathione.  Extensive research on animals has shown that glutathione exerts protective action in the liver,” Wikipedia.   Averaging 6 days a week, I use a short-term fast (from about 7 PM until 11 AM).  I have more energy by skipping breakfast and using my stored fat.  If you want to know more, then go to my website and use the internal Google Search Engine to read the journal articles and my articles with links to them.  You should watch the documentaries and lectures on YouTube.  I have a video page on my site which has links and a description of the best of those documentaries and lectures on diet, type-2 diabetes, CVD, bad pharma, psychiatric drugs, and other issues related to health.  Dr. Jason Fung is the best authority of diet and how to fix the results of bad diet by fasting.  He has numerous lectures on YouTube, and his book The Obesity Code and his Complete Guide to Fasting are above all others.   For inspiration I recommend reading the testimonial by Reyn’s wife on her very ill husband.  As recommended by Dr. Fung, Reyn did alternate day fasting with a very low carb diet (replaced with natural fats, not vegetable oils), and he regained his health. 

Nothing is simple about our biological systems.  This is true for foods and dieting.  I have set down very short-simple answers:  sugar (sucrose), which is half fructose is in excess is white poison; it damages every tissue in the body, especially the liver.  The damaged liver causes higher than normal blood insulin, called insulin resistance which drives weight gain by increasing fat storage.  Obesity is a problem with the fat-storage system driven by high insulin.  Too much fat in the pancreas causes T2D.  The fix is through staying in the fat burning mode by fasting, and eating more natural fat and thus less carbs.  Take time to visit my video page  Knowledge is power; a power a corporate media and its advertisers oppose by recommending “eat less and exercise more”.  


On curing type-2 diabetes with diet. 37 min, 15,00 views (2/16) Jason Fung.

The advice here is merely what JK would do in those situations. See your doctor for medical advice.

The only thing necessary for the triumph of evil is for good men to do nothing--Edmond Burke

Perverse systems grow by recruiting good men--jk

Everybody thinks they know what good is, but they are confused--Plato