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#42 RHYMED POEMS SOCIAL
MESSAGE
e-mail to thinker@skeptically.org There is an alarming laxity in the production of research, education of public and doctors, and standards
of FDA approval for drugs, as well as the monitoring of safety and effectiveness of drugs.
For 2 chapters of the best book on how big PHARMA has manipulated the above and much more by Doctor Marcia Angell (Harvard Professor and former
editor of New England Journal of Medicine). |
Drugs are tested by the people who manufacture
them, in
poorly designed trials, on hopelessly small numbers of weird, unrepresentative
patients, and analysed using techniques which are flawed by design, in such a
way that they exaggerate the benefits of treatments. Unsurprisingly, these
trials tend to produce results that favour the manufacturer. When trials throw
up results that companies don't like, they are perfectly entitled to hide them
from doctors and patients, so we only ever see a distorted picture of any
drug's true effects. Regulators see most of the trial data, but only from early
on in a drug's life, and even then they don't give this data to doctors or
patients, or even to other parts of government. This distorted evidence is then
communicated and applied in a distorted fashion. In their forty years of
practice after leaving medical school, doctors hear about what works through ad
hoc oral traditions, from sales reps, colleagues or journals. But those
colleagues can be in the pay of drug companies – often undisclosed – and the
journals are too. And so are the patient groups. And finally, academic papers,
which everyone thinks of as objective, are often covertly planned and written
by people who work directly for the companies, without disclosure. Sometimes
whole academic journals are even owned outright by one drug company. Aside from
all this, for several of the most
important and enduring problems in medicine, we have no idea what the best
treatment is, because it's not in anyone's financial interest to conduct any
trials at all. These are ongoing problems, and although people have claimed to
fix many of them, for the most part they have failed; so all these problems
persist, but worse than ever, because now people can pretend that everything is
fine after all.
Prof. Ben Goldacre, MD, Bad Pharma, Page
XI, Nov. 2012
Medical
science is like a minefield where industry tobacco science is buried beneath
the façade of science, and there are only indirect signs of industry
sponsorship.
Enter secondary content here
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Enter supporting content here Those who have a financial interest in the outcome manipulate the results, Major study finds that all 37 journal articles positive effects over stated; the average was 32%. |