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Home | Why Physicians Give Junk Treatments | FDA is an Extensionof Pharma, Insider's Expose' | Quotes on Bad Pharma | Half of Drugs are Useless or Dangerous | Why We Can't Trust Clinical Guidelines | American Heart Association and Industries | Continuing Medical Education is Marketing | Why We Can't Trust Journal Articles--Bias | Causes of Deaths:" Psychiatric-drugs 3rd place after cancer and heart attacks | Government Facade Clinical Trial Reporting | Fixing Pharma to Serve the Public | Pharma Crimes Prosecuted, the Major Court Settlements | Neurontin, an example of off-label marketing | How Pharma Funds Then Runs Clinical Trials, an example | Half of Clinical Trials are Unpublished, burying negative results | |||
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Enter supporting content here
A thought experiment: Think like the Pfizer CEO (a marketing
expert whose job review by his board of directors is based upon your maximization
of quarterly profits). You know
how to work Pfizer-friendly FDA. New drugs are approved
based on a phase III trials showing
in a select young population some SHORT-TERM benefit for their condition
(compared to nothing at all, a sugar pill); they have the least side
effects. You then expand usage on the
basis of testing with junk marketing science in “phase IV studies”. Your
marketing department edits the results
to be published. The journals never
receive the raw data, thus you manipulate the result to promote sales. Your
pay noted experts to educate
doctors in required continuing education class about the benefits for these newly
discovered off-label usages. Your sales reps repeat the message. Such
claims based on junk science are
protected by the Free Speech Clause of the Constitution. No FDA approval
for the new usage is needed if your company doesn’t advertise the new
usage. Over 70% of Pfizer's sales are
for off-label usages. You purchase
prescribing records of doctors from data mining companies so that you can funnel
thousands of dollars for “services” to doctors who push your drugs. You
schmooze with “donations” politicians,
regulators, health care administrators, medical schools, and medical
organizations—money well invested. For
example, The American Heart Association establishes treatment guidelines based
on the junk science of Pfizer and others.
Civil courts plus administrators in hospitals and clinics pressure the doctors
to follow those guidelines. You also
mount advertising blitzes to educate the public about Pfizer’s drugs that will
be taken long-term. In these 30 second
TV educationals, you exaggerate disease risks, hype benefits, and merely
list risks as required by the FDA. Your
company will reward you with millions in stock options. See Side Effects and Marketing Science for an “ad
nausea” account of pharma.
All this is confirmed by Harvard Prof. Marcia Angell in The
Truth About Drug Companies.
INTERNAL SITE SEARCH ENGINE by Google
Disclaimer:
The information, facts, and opinions
provided here is not a substitute for professional advice. It only indicates
what JK believes, does, or
would do. Always consult your primary
care physician for medical advice, diagnosis, and treatment.
Positive bias averaged
32% (range 11 to 69%) in a NEJM article, 2008.
The study of neuroleptic drugs made a comparison of 74 journal articles
to the raw data which was obtained by FOIA (Freedom of Information Act) from
the FDA. See http://healthfully.org/index/id9.html,
or http://content.nejm.org/cgi/content/short/358/3/252
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