Home | Aspirin prevents MI, Cancer & Alzheimer's--a summary--jk | Aspirin-prevents-cancer-heart-attacks-Alzheimer's | Aspirin, various benefits | ASPIRIN: HISTORY & USES | Aspirin reduces cancer Metastasis, survival up 67% | Aspirin: UK study finds major reduction in cancer death | Breast Cancer Aspirin, Harvard Nurses' Study, complete | ALL NON-ASPIRIN NSAIDS INCREASE MI | American Heart Association warns NSAIDs cause MI | Aspirin reduces cancer risk | Aspirin mechanism cancer survival | aspirin & cancer, mechanism, etc. | NAPROXIN CAUSED 50% more CORONARY events than placebo | Reyes Syndrome--PhARMA's attack upon aspirin | Aspirin reduces C-recative Protein (MI reduction) | Alzheimer's Disease Risk Reduced 60% | ASPIRIN COATED SAFER THAN OTHER NSAIDS | More articles on various benefits of ASPIRIN | Understanding thrombi & coagulation | ASPIRIN REDUCES CORONARY THROMBOSIS 51% | ASPIRIN BEFORE BYPASS SURGERY SAVES LIVES | ASPIRIN BEST FOR THOSE WITH BYPASS | HOW ASPIRIN PROTECTS AGAINST COLON CANCER | Aspirin reduces risk of colon cancer 50% | The more you take the lower the risk of colon cancer | VIOXX mechanism (COX-1 & 2) explained | Why COX-2 inhibitors (VIOXX) kill, mechanism explained | VIOXX, brothers, PROFITS: the aspirin alternatives | Prexige works like asprin and VIOXX | WHICH NSAID, IBUPROFIN OR ASPIRIN? | WOMEN BENEFITS, breast cancer and C-sections | ASPIRIN PREVENTS PREGNANCY COMPLICATION | Alzheimer's Drug, Aricpet, avoid | WARFARIN and COUMADIN warnings

ASPIRIN: the best NSAID

Don't be a DODO, take an aspirin a day!
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Alan Aldridge

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JK has been taking an average of two 325 mg aspirin a day since 1991 because it reduces  


the leading form of cancer 

COLORECTAL CANCER 63%

PANCREATIC CANCER 53%

LUNG CANCER 36%

PROSTATE CANCER 39%

breast cancer 39%

Stomach 62%

ovarian cancer 47%

esophageal 73%

Hodgkin's lymphoma 60%

ALZHEIMERS 73% 

Promotes cancer survival -- for stage I, II, & III breast cancer 67% (id/26), for colon cancer 51%, and other adenocarcinomas.  

Reduced
risk for Hodgkin's disease, skin and bladder cancers, and adult leukemia 

Other conditions:  Alzheimer's 73%, lowers risk of ALS,  



Cuts in half the level of C-reactive protein (released by immune system during an infection, and associated with MI), and in larger amounts reduces MI in high risk population 51%.






Two new papers which develop the benefits of aspirin, aspirin’s
cancer protection
and  Aspirin inhibits atherosclerosis
which is the causes over 90% of the cases of hypertension and over 80% of
the acute heart attacks. 







THE LARGER THE DOES THE GREATER THE PROTECTION, effects take several years since aspirin only promotes the death (apoptosis) of abnormal cells.  The second know method of action is through COX-2 inhibition.  Over-expression of COX-2 and increased prostaglandin biosynthesis correlates with carcinogensis and metastasis at most anatomic sites.  



  


Stomach bleeding is greatly reduced by using coated aspirin. 


In properly controlled, fair studies the risk of stomach bleeding is about equal.  And for the low dose in prophalitic use, (not the much higher does for pain management) the risk is slight--about, less than one per year per 1,000. 



 


Goodman & Gilman, 11th Ed. P. 690:  “Although aspirin is regarded as the standard against which other drugs should be compared for treatment of rheumatoid arthritis, many clinicians favor the use of other NSAIDs perceived to have better gastrointestinal tolerability, even though this perception remains unproven by convincing clinical trials.” 


{As I pointed out, most test use a a low does of a coated NSAID compared to an uncoated aspirin.--jk}


 


It has come to light in 05 that all the NSAIDs but aspirin increase the risk of heart attacks and strokes by accelerating the rate of plaque formation (viz. arteriosclerosis)—a fact few doctors are aware of.


 


Big PhARMA has attacked aspirin usage through two principle routes, stomach bleeds and Reyes Syndrome --both are a smear job.  They have trained doctors to state that if there is a stomach bleed and aspirin is used (including the low dose) that aspirin is the cause.  The bacteria Pylori has been established as the cause of stomach and duodenum ulcers.  Yet when aspirin is used (almost always with other drugs), the cause is attributed to aspirin.  As for Reyes Syndrome, once a laboratory (rather than symptomatic) method of diagnosis was established, the association with aspirin approached zero (2 per year), yet nearly all doctors believe it is a significant health risk for children.  

For pregnant women, reduces C-section 400% by lowering incidence of hypertension.

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Todd Schorr

Aspirin:  It is more of a miracle than penicillin; what has changed is the control pharma exerts. Its major unexpected health benefits were discovered  in the 60s through 90s.  It has the highest cure rate of all chemotherapies for stage I, II, and III,  and is also best at preventing cancer.  Aspirin promotes the apoptosis (death) of abnormal cells through stimulation of various necrosis factors and inhibition of JNK which “regulates several important cellular functions including cell growth, differentiation, survival and apoptosis”  Wiki.   A large collection of journal articles are pasted at http://healthfully.org/aspirin/ & http://healthfully.org/nsaids/.  The past below is from an article prepared by JK at  http://healthfully.org/rc/id3.html; its section on cancer:

 

BREAST CANCER SURVIVAL UP 66% by stimulating necrosis factor TNF—above. Colon cancer survival increased 74%, others.  Mechanism: COX-2 which is associated with increased prostaglandin biosynthesis which correlates to metastasis and carcinogenesis, and aspirin blocks COX-2, thereby reducing risk, plus promotes death of abnormal cells (below).     

CANCERS VARIOUS TISSUES RISK: reduction of63% colon, 39% breast, 36% lung, and 39% prostate cancer. Significant risk reductions were also observed for esophageal 73%, stomach 62%, and ovarian cancer 47%” also.  Epidemiologic studies of malignant melanoma, Hodgkin's disease, and adult leukemia also found that NSAIDs are protective; melanoma 55%.  Other studies have shown that aspirin promotes the death of abnormal cells through the natural mechanism of apoptosis by stimulating tumor necrosis factor NF-B, by p38 & JNK.  Long term, but low dose is insufficient. 

 

The increased survival of breast cancer can be extended to the other glandular, blood, & epithelial cancers.

 

The lack of dissemination of information and the failure to investigate further is a result of corporate medicine and our corporatist state.  Add to that aspirin protection from & treatment of cardiovascular disease, MI, Strokes, Alzheimer’s and ALS, rheumatoid and osteoarthritis; this proves that aspirin is clearly the best of all drugs.  Everyone over the age of 25 should be taking prophylactically a 325 mg uncoated aspirin in the morning and another in the evening.  It anti-inflammatory slows atherogenesis and the resultant cardiovascular disease; that by itself justifies daily usage.  Aspirin was the standard arthritic treatment at much higher dose (3 to 7.5 gm daily, Merck Manual 1987).  The overblown concern for stomach ulcers is the working of pharma, which  ignores the role of pylori bacteria.  The 800 pound gorilla (a phrase used by Harvard Prof. Marcia Angell, MD) has too long used its tobacco ethics.      





Disclaimer:  The information, facts, and opinions provided here is not a substitute for professional advice.  It only indicates what JK believes, does, or would do.  Always consult your primary care physician for any medical advice, diagnosis, and treatment. 




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There is grass root revulsion to the current corporate health industry, with pharma doing the most harm.  The best account of bad pharma is by Danish Prof. Peter Gotzsche in his 2013 book Deadly Medicine and Organised Crime:  How big pharma has corrupted healthcare.  Prof. Gotzsche’s book has won the British Medical Book Award given by the BMA (British Medical Association which is comparable to our AMA).  Further endorsement comes from the Richard Smith former Editor-in-Chief of the BMJ (British Medical Journal) and Drummond Rennie, Deputy Editor of JAMA (Journal of American Medical Association) which are 2 of the 4 leading English medical journal.   The President’s Lecture on YouTube by Harvard Professor Marcia Angell confirms Prof. Gotzsche’s book. Pharma is worse than you can imagine.       




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There is an alarming laxity in the production of research, education of public and doctors, and standards of FDA approval for drugs, as well as the monitoring of safety and effectiveness of drugs.  For 2 chapters of the best book on how big PHARMA has manipulated the above and much more by Doctor Marcia Angell (Harvard Professor and former editor of New England Journal of Medicine).

 

 
 
 

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http://www.sciam.com/podcast/episode.cfm?id=body-makes-own-aspirin-compound-09-01-08&sc=WR_20090113

Why aspirin is so safe.  The other NSAIDs have serious side effects which pharma hides.  For example acetaminophen (http://healthfully.org/bta/) is strong associated with asthma and liver failure

Body Makes Own Aspirin Compound


A study in the Journal of Agricultural and Food Chemistry finds that humans can manufacture their own salicylic acid, the major part of aspirin. Another study, in Nature, shows that plants make their own salicylic acid at wound sites. Karen Hopkin reports


Aspirin is a popular painkiller, and chances are you have some in your medicine chest right now. You might even have some in your flesh-and-blood, put-a-shirt-on-it chest. Because a new study suggests that humans can make their own salicylic acid, which forms the bulk of aspirin’s active ingredient.

Scientists at Scotland’s National Health Service previously observed that people can have salicylic acid in their blood even if they haven’t recently swallowed an aspirin. Vegetarians have really high concentrations, which makes sense, given that plants make salicylic acid, so fruits and veggies are full of it. But their recent study suggests that not all of the chemical comes from the diet, because humans can take a precursor molecule and turn it into salicylic acid—results published in the Journal of Agricultural and Food Chemistry.

The researchers say that people might make salicylic acid to fight inflammation or disease…which would also make sense…because plants make the stuff to fight off infections. In fact, a recent study published online in the journal Nature shows how calcium released at the site of an infection tells plants to ramp up production of the protective compound. Just Mother Nature’s way of saying, “Make two aspirin and call me when you flower.”

—Karen Hopkin 

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Disclaimer:  The information, facts, and opinions provided here is not a substitute for professional advice.  It only indicates what JK believes, does, or would do.  Always consult your primary care physician for any medical advice, diagnosis, and treatment.